Studies on Mammotrophic Action of Sulpiride
نویسندگان
چکیده
منابع مشابه
Studies on intestinal absorption of sulpiride (3): intestinal absorption of sulpiride in rats.
The aim of this study was to investigate whether the concomitant administration of the substrates or inhibitors of PEPT1, OCTN1, OCTN2, and P-glycoprotein affects the intestinal absorption of sulpiride in rats. The absorption of sulpiride from rat intestine was decreased by the substrates or inhibitors of PEPT1, OCTN1, and OCTN2. On the other hand, the absorption was increased by the substrates...
متن کاملStudies on intestinal absorption of sulpiride (1): carrier-mediated uptake of sulpiride in the human intestinal cell line Caco-2.
We investigated whether the uptake of a specific antipsychotic agent, sulpiride, in Caco-2 cells is mediated by a carrier-mediated system. Caco-2 cell monolayers were cultured in plastic culture dishes and uptake and efflux studies were conducted. The determination of sulpiride was performed by HPLC. At 37 degrees C, sulpiride uptake in pH 6.0 was twice as much as in pH 7.4. At 4 degrees C, how...
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ژورنال
عنوان ژورنال: The Journal of Kansai Medical University
سال: 1977
ISSN: 0022-8400
DOI: 10.5361/jkmu1956.29.4_746